Brothers John and Matt have inherited an island cabin from their lately deceased uncle. Together with Matt’s girlfriend, Nicki, and different mutual associates, the siblings journey to the cabin for a soothing weekend getaway. However, not lengthy after arriving, the group is besieged by ravenous canines. They watch in horror as one other vacationer, Luke, is eaten alive. Quickly, they uncover a coaching facility the place the canines have been bred to kill.